A RNA methylation in mind growth and ailments

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Epitranscriptomic regulation by m 6 A RNA methylation in mind growth and ailments

 

  • Mobile RNAs are pervasively tagged with numerous chemical moieties, collectively known as epitranscriptomic modifications. The methylation of adenosine at N6place generates N6-methyladenosine (m6A), which is essentially the most ample and reversible epitranscriptomic modification in mammals.
  • The m6A signaling is mediated by a devoted set of proteins comprised of writers, erasers, and readers. Opposite to the activation-repression binary view of gene regulation, rising proof means that the m6A methylation controls a number of elements of mRNA metabolism, akin to splicing, export, stability, translation, and degradation, culminating within the fine-tuning of gene expression.
  • Mind exhibits the best abundance of m6A methylation within the physique, which is developmentally altered. Inside the mind, m6A methylation is biased towards neuronal transcripts and delicate to neuronal exercise. In a wholesome mind, m6A maintains a number of developmental and physiological processes akin to neurogenesis, axonal development, synaptic plasticity, circadian rhythm, cognitive perform, and stress response. The m6A imbalance contributes to the pathogenesis of acute and continual CNS insults, mind most cancers, and neuropsychiatric problems.

 

  • This overview mentioned the molecular mechanisms of m6A regulation and its implication within the developmental, physiological, and pathological processes of the mind.

 

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GNAS Complex Locus (GNAS) Antibody

20-abx214658
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  • 100 ul
  • 50 ul

GNAS Complex Locus (GNAS) Antibody

20-abx338380
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GNAS Antibody

32899-100ul 100ul
EUR 302.4

GNAS antibody

38452 100ul
EUR 439

GNAS antibody

38452-100ul 100ul
EUR 302.4

GNAS Antibody

E10-30780 100ul
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

E10-30780T 100ul
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

E10-30781 100ul
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

E10-30781T 100ul
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

E19-7068 100μg/100μl
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

E19-7388 100μg/100μl
EUR 225
Description: Available in various conjugation types.

GNAS Antibody

DF7068 200ul
EUR 420

GNAS Antibody

DF7068-100ul 100ul
EUR 280

GNAS Antibody

DF7068-200ul 200ul
EUR 350

GNAS Antibody

DF7388 200ul
EUR 420

GNAS Antibody

DF7388-100ul 100ul
EUR 280

GNAS Antibody

DF7388-200ul 200ul
EUR 350

GNAS Antibody

E92732 100ul
EUR 255
Description: Available in various conjugation types.

GNAS Antibody

E91416 100μg
EUR 255
Description: Available in various conjugation types.

GNAS Antibody

E95546 100μg
EUR 255
Description: Available in various conjugation types.

GNAS Antibody

CAC11323-100ug 100ug
EUR 314

GNAS Antibody

CAC11323-50ug 50ug
EUR 199.2

GNAS Antibody

CAC10438-100ug 100ug
EUR 314

GNAS Antibody

CAC10438-50ug 50ug
EUR 199.2

GNAS antibody

70R-12940 100 ul
EUR 550
Description: Affinity purified Rabbit polyclonal GNAS antibody

GNAS antibody

70R-13520 100 ul
EUR 550
Description: Affinity purified Rabbit polyclonal GNAS antibody

GNAS antibody

70R-1643 100 ug
EUR 407
Description: Rabbit polyclonal GNAS antibody raised against the N terminal of GNAS

GNAS antibody

70R-1651 100 ug
EUR 407
Description: Rabbit polyclonal GNAS antibody raised against the C terminal of GNAS

GNAS antibody

70R-1652 100 ug
EUR 407
Description: Rabbit polyclonal GNAS antibody raised against the N terminal of GNAS

GNAS antibody

70R-21619 50 ul
EUR 289
Description: Rabbit polyclonal GNAS antibody

GNAS antibody

70R-5756 50 ug
EUR 467
Description: Rabbit polyclonal GNAS antibody raised against the N terminal of GNAS

GNAS Antibody

1-CSB-PA009596GA01HU
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  • 150ul
  • 50ul
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

GNAS Antibody

1-CSB-PA247539
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  • 100ul
  • 50ul
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

GNAS Antibody

1-CSB-PA307619LA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500

GNAS Antibody

1-CSB-PA352389LA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

GNAS Antibody

1-CSB-PA147947
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  • 100ul
  • 50ul
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

GNAS Antibody

ABD7068 100ug
EUR 325

GNAS Antibody

ABD7388 100ug
EUR 325

GNAS Antibody

F40026-0.4ML 0.4 ml
EUR 322.15
Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Alternative splicing of downstream exons of the GNAS gene is observed, which results in different forms of the stimulatory G protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors.

GNAS Antibody

GWB-60D8A8 0.1 mg Ask for price

GNAS Antibody

GWB-DFA7EE 0.1 mg Ask for price

GNAS Antibody

GWB-MN943G 100ug Ask for price

GNAS Antibody

GWB-MP242H 50ug Ask for price

GNAS Antibody

R35181-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Guanine nucleotide binding protein alpha stimulating activity polypeptide 1

GNAS Antibody

MBS7107179-005mg 0.05mg
EUR 190

GNAS Antibody

MBS7107179-01mg 0.1mg
EUR 270

GNAS Antibody

MBS7107179-5x01mg 5x0.1mg
EUR 1205

GNAS Antibody

MBS7123704-005mL 0.05mL
EUR 190

GNAS Antibody

MBS7123704-01mL 0.1mL
EUR 270

GNAS Antibody

MBS7123704-5x01mL 5x0.1mL
EUR 1205

GNAS Antibody

MBS7123705-005mL 0.05mL
EUR 190

GNAS Antibody

MBS7123705-01mL 0.1mL
EUR 270

GNAS Antibody

MBS7123705-5x01mL 5x0.1mL
EUR 1205

GNAS Antibody

MBS7006626-005mg 0.05mg
EUR 190

GNAS Antibody

MBS7006626-01mg 0.1mg
EUR 270

GNAS Antibody

MBS7006626-5x01mg 5x0.1mg
EUR 1205

GNAS antibody

MBS9412789-005mL 0.05mL
EUR 300

GNAS antibody

MBS9412789-01mL 0.1mL
EUR 390

GNAS antibody

MBS9412789-5x01mL 5x0.1mL
EUR 1610

GNAS Antibody

MBS9413173-005mL 0.05mL
EUR 300

GNAS Antibody

MBS9413173-01mL 0.1mL
EUR 390

GNAS Antibody

MBS9413173-5x01mL 5x0.1mL
EUR 1610

GNAS Antibody

MBS8516510-01mg 0.1mg
EUR 305

GNAS Antibody

MBS8516510-01mLAF405L 0.1mL(AF405L)
EUR 465

GNAS Antibody

MBS8516510-01mLAF405S 0.1mL(AF405S)
EUR 465

GNAS Antibody

MBS8516510-01mLAF610 0.1mL(AF610)
EUR 465

GNAS Antibody

MBS8516510-01mLAF635 0.1mL(AF635)
EUR 465

GNAS Antibody

MBS8516821-01mg 0.1mg
EUR 305

GNAS Antibody

MBS8516821-01mLAF405L 0.1mL(AF405L)
EUR 465

GNAS Antibody

MBS8516821-01mLAF405S 0.1mL(AF405S)
EUR 465

GNAS Antibody

MBS8516821-01mLAF610 0.1mL(AF610)
EUR 465

GNAS Antibody

MBS8516821-01mLAF635 0.1mL(AF635)
EUR 465

GNAS Antibody

MBS8500866-01mg 0.1mg
EUR 325

GNAS Antibody

MBS8500866-01mLAF405L 0.1mL(AF405L)
EUR 565

GNAS Antibody

MBS8500866-01mLAF405S 0.1mL(AF405S)
EUR 565

GNAS Antibody

MBS8500866-01mLAF610 0.1mL(AF610)
EUR 565

GNAS Antibody

MBS8500866-01mLAF635 0.1mL(AF635)
EUR 565

GNAS Antibody

MBS8503174-01mL 0.1mL
EUR 325

GNAS Antibody

MBS8503174-01mLAF405L 0.1mL(AF405L)
EUR 565

GNAS Antibody

MBS8503174-01mLAF405S 0.1mL(AF405S)
EUR 565

GNAS Antibody

MBS8503174-01mLAF610 0.1mL(AF610)
EUR 565

GNAS Antibody

MBS8503174-01mLAF635 0.1mL(AF635)
EUR 565

GNAS Antibody

MBS8504502-01mg 0.1mg
EUR 325

GNAS Antibody

MBS8504502-01mLAF405L 0.1mL(AF405L)
EUR 565

GNAS Antibody

MBS8504502-01mLAF405S 0.1mL(AF405S)
EUR 565

GNAS Antibody

MBS8504502-01mLAF610 0.1mL(AF610)
EUR 565

GNAS Antibody

MBS8504502-01mLAF635 0.1mL(AF635)
EUR 565

GNAS Antibody

MBS2520647-006mL 0.06mL
EUR 190

GNAS Antibody

MBS2520647-012mL 0.12mL
EUR 265

GNAS Antibody

MBS2520647-02mL 0.2mL
EUR 415

GNAS Antibody

MBS2520647-5x02mL 5x0.2mL
EUR 1835

GNAS Antibody

MBS5312039-01mL 0.1mL
EUR 1070

GNAS Antibody

MBS5312039-5x01mL 5x0.1mL
EUR 4655

GNAS Antibody

MBS5312409-01mL 0.1mL
EUR 1070

GNAS Antibody

MBS5312409-5x01mL 5x0.1mL
EUR 4655

GNAS Antibody

MBS9607721-01mL 0.1mL
EUR 260

GNAS Antibody

MBS9607721-02mL 0.2mL
EUR 305

GNAS Antibody

MBS9607721-5x02mL 5x0.2mL
EUR 1220

GNAS Antibody

MBS9608025-01mL 0.1mL
EUR 260

GNAS Antibody

MBS9608025-02mL 0.2mL
EUR 305

GNAS Antibody

MBS9608025-5x02mL 5x0.2mL
EUR 1220

GNAS Complex Locus (GNAS) Antibody (HRP)

20-abx337231
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GNAS Complex Locus (GNAS) Antibody (FITC)

20-abx337232
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GNAS Complex Locus (GNAS) Antibody (Biotin)

20-abx337233
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

anti- GNAS antibody

FNab03536 100µg
EUR 606.3
Description: Antibody raised against GNAS

GNAS Antibody (HRP)

20-abx306647
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GNAS Antibody (FITC)

20-abx306648
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

NESP55,GNAS Antibody

abx235663-100ug 100 ug
EUR 577.2

GNAS Antibody (Biotin)

20-abx306649
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

NESP55,GNAS Antibody

abx235663-100g 100 µg
EUR 350

GNAS Antibody (Center)

MBS9214398-008mL 0.08mL
EUR 210

GNAS Antibody (Center)

MBS9214398-04mL 0.4mL
EUR 430

GNAS Antibody (Center)

MBS9214398-5x04mL 5x0.4mL
EUR 1910

GNAS complex locus (GNAS) polyclonal antibody

ABP-PAB-11314 100 ug Ask for price

GNAS Antibody (Ascites)

MBS9200490-01mL 0.1mL
EUR 430

GNAS Antibody (Ascites)

MBS9200490-5x01mL 5x0.1mL
EUR 1910

GNAS Antibody (C-term)

MBS9205942-008mL 0.08mL
EUR 210

GNAS Antibody (C-term)

MBS9205942-04mL 0.4mL
EUR 430

GNAS Antibody (C-term)

MBS9205942-5x04mL 5x0.4mL
EUR 1910

GNAS Antibody (N-Term)

MBS9215820-005mL 0.05mL
EUR 210

GNAS Antibody (N-Term)

MBS9215820-02mL 0.2mL
EUR 430

GNAS Antibody (N-Term)

MBS9215820-5x02mL 5x0.2mL
EUR 1910

GNAS Antibody (C-term)

MBS9203183-008mL 0.08mL
EUR 210

GNAS Antibody (C-term)

MBS9203183-04mL 0.4mL
EUR 430

GNAS Antibody (C-term)

MBS9203183-5x04mL 5x0.4mL
EUR 1910

anti- NESP55,GNAS antibody

FNab05663 100µg
EUR 606.3
Description: Antibody raised against NESP55,GNAS

Anti-NESP55,GNAS antibody

PAab05663 100ug
EUR 245

GNAS Antibody, HRP conjugated

1-CSB-PA307619LB01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

GNAS Antibody, HRP conjugated

1-CSB-PA352389LB01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

GNAS Antibody, HRP conjugated

MBS7107180-005mg 0.05mg
EUR 190

GNAS Antibody, HRP conjugated

MBS7107180-01mg 0.1mg
EUR 270

GNAS Antibody, HRP conjugated

MBS7107180-5x01mg 5x0.1mg
EUR 1205

GNAS Antibody; HRP conjugated

MBS7003350-005mg 0.05mg
EUR 190

GNAS Antibody; HRP conjugated

MBS7003350-01mg 0.1mg
EUR 270

GNAS Antibody; HRP conjugated

MBS7003350-5x01mg 5x0.1mg
EUR 1205

GNAS Antibody, FITC conjugated

1-CSB-PA307619LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

GNAS Antibody, FITC conjugated

1-CSB-PA352389LC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

GNAS Antibody, FITC conjugated

MBS7107181-005mg 0.05mg
EUR 190

GNAS Antibody, FITC conjugated

MBS7107181-01mg 0.1mg
EUR 270

GNAS Antibody, FITC conjugated

MBS7107181-5x01mg 5x0.1mg
EUR 1205

GNAS Antibody; FITC conjugated

MBS7004175-005mg 0.05mg
EUR 190

GNAS Antibody; FITC conjugated

MBS7004175-01mg 0.1mg
EUR 270

GNAS Antibody; FITC conjugated

MBS7004175-5x01mg 5x0.1mg
EUR 1205

OAAN01353-50UL - GNAS Antibody

OAAN01353-50UL 50ul
EUR 149

Polyclonal GNAS Antibody (Center)

APR05815G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GNAS (Center). This antibody is tested and proven to work in the following applications:

GNAS Antibody, Biotin conjugated

1-CSB-PA307619LD01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

GNAS Antibody, Biotin conjugated

1-CSB-PA352389LD01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against GNAS. Recognizes GNAS from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

OAAN01353-100UL - GNAS Antibody

OAAN01353-100UL 100ul
EUR 249

OAAN01353-200UL - GNAS Antibody

OAAN01353-200UL 200ul
EUR 389

OAAJ07854-100UL - GNAS Antibody

OAAJ07854-100UL 100uL
EUR 319

OAGA00440-100UL - GNAS antibody

OAGA00440-100UL 100ul
EUR 369

OAGA00997-100UL - GNAS antibody

OAGA00997-100UL 100ul
EUR 369

GNAS Antibody, Biotin conjugated

MBS7107182-005mg 0.05mg
EUR 190

GNAS Antibody, Biotin conjugated

MBS7107182-01mg 0.1mg
EUR 270

GNAS Antibody, Biotin conjugated

MBS7107182-5x01mg 5x0.1mg
EUR 1205

GNAS Antibody; Biotin conjugated

MBS969903-005mg 0.05mg
EUR 190

GNAS Antibody; Biotin conjugated

MBS969903-01mg 0.1mg
EUR 270

GNAS Antibody; Biotin conjugated

MBS969903-5x01mg 5x0.1mg
EUR 1205

Rabbit Polyclonal antibody to GNAS (GNAS complex locus)

TA308888 100 µl Ask for price

Rabbit Polyclonal antibody to GNAS (GNAS complex locus)

TA308889 100 µl Ask for price

GNAS Polyclonal Antibody

A64422
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  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

GNAS Polyclonal Antibody

A68803
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  • 100 ?g
  • 20 ul
  • 50 ul
  • 100 ul

GNAS Conjugated Antibody

C32899 100ul
EUR 476.4

GNAS Polyclonal Antibody

E-AB-14088-120uL 120uL
EUR 240
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-14088-200uL 200uL
EUR 399
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-14088-20uL 20uL
EUR 73
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-14088-60uL 60uL
EUR 143
Description: Unconjugated

GNAS Polyclonal Antibody

MBS126335-002mL 0.02mL
EUR 200

GNAS Polyclonal Antibody

MBS126335-005mL 0.05mL
EUR 255

GNAS Polyclonal Antibody

MBS126335-01mL 0.1mL
EUR 345

GNAS Polyclonal Antibody

MBS126335-02mL 0.2mL
EUR 545

GNAS Polyclonal Antibody

MBS126335-5x02mL 5x0.2mL
EUR 2265

GNAS Polyclonal Antibody

E-AB-61003-120uL 120uL
EUR 320
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-61003-200uL 200uL
EUR 530
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-61003-60uL 60uL
EUR 200
Description: Unconjugated

GNAS Polyclonal Antibody

E-AB-61003-each each Ask for price
Description: Unconjugated

GNAS Polyclonal Antibody

MBS9126568-002mL 0.02mL
EUR 200

GNAS Polyclonal Antibody

MBS9126568-005mL 0.05mL
EUR 255

GNAS Polyclonal Antibody

MBS9126568-01mL 0.1mL
EUR 345

GNAS Polyclonal Antibody

MBS9126568-02mL 0.2mL
EUR 545

GNAS Polyclonal Antibody

MBS9126568-5x02mL 5x0.2mL
EUR 2265

GNAS Polyclonal Antibody

MBS2524331-002mL 0.02mL
EUR 135

GNAS Polyclonal Antibody

MBS2524331-006mL 0.06mL
EUR 190

GNAS Polyclonal Antibody

MBS2524331-012mL 0.12mL
EUR 265

GNAS Polyclonal Antibody

MBS2524331-02mL 0.2mL
EUR 415

GNAS Polyclonal Antibody

MBS2524331-5x02mL 5x0.2mL
EUR 1835

RNA-Binding Proteins in Most cancers: Practical and Therapeutic Views

 

RNA-binding proteins (RBPs) crucially regulate gene expression by post-transcriptional regulation, akin to by modulating microRNA (miRNA) processing and the choice splicing, different polyadenylation, subcellular localization, stability, and translation of RNAs. Greater than 1500 RBPs have been recognized so far, and plenty of of them are recognized to be deregulated in most cancers. Alterations within the expression and localization of RBPs can affect the expression ranges of oncogenes, tumor-suppressor genes, and genome stability-related genes.

RBP-mediated gene regulation can result in numerous cancer-related mobile phenotypes, akin to proliferation, apoptosis, angiogenesis, senescence, and epithelial-mesenchymal transition (EMT)/invasion/metastasis. This regulation can be related to most cancers prognosis.

Thus, RBPs could be potential targets for the event of therapeutics for the most cancers therapy. On this overview, we describe the molecular features of RBPs, their roles in cancer-related mobile phenotypes, and numerous approaches that could be used to focus on RBPs for most cancers therapy.

 

Circulating Lengthy Non-Coding RNA GAS5 Is Overexpressed in Serum from Osteoporotic Sufferers and Is Related to Elevated Danger of Bone Fragility

 

Osteoporosis (OP) is a multifactorial dysfunction through which environmental elements together with genetic variants and epigenetic mechanisms have been implicated. Lengthy non-coding RNAs (lncRNAs) have just lately emerged as essential regulators of bone metabolism and OP aetiology.

On this research, we analyzed the expression degree and the genetic affiliation of lncRNA GAS5 in OP sufferers in comparison with controls. Quantitative RT-PCR evaluation of GAS5 was carried out on the serum of 56 OP sufferers and 28 wholesome people. OP topics had been divided into three teams of research: 29 with fragility fractures of lumbar backbone (OP_VF), 14 with fragility fractures of femoral neck (OP_FF) and 13 with out fractures (OP_WF). Genotyping of the rs145204276 insertion/deletion polymorphism has additionally been carried out by Restriction fragment size polymorphism (RFLP) and direct sequencing analyses.

Expression of circulating GAS5 is considerably elevated in OP sufferers in comparison with controls (p < 0.01), with a statistically greater significance in fractured OP people vs. wholesome topics (p < 0.001). No statistically important change was present in feminine OP sufferers; conversely, GAS5 is upregulated within the subgroup of fractured OP ladies sera (p < 0.01) and in all OP males (p < 0.05). Moreover, a direct correlation between GAS5 expression degree and parathyroid hormone (PTH) focus was present in OP sufferers (r = 0.2930; p = 0.0389).

Genetic evaluation of rs145204276 revealed that the deletion allele was correlated with the next expression of GAS5 in OP sufferers (0.22 ± 0.02 vs. 0.15 ± 0.01, ** p < 0.01). Our outcomes recommend circulating GAS5 as a putative biomarker for the prognosis and prognosis of OP and OP-related fractures.

 

SOX2 Antibody

25044 100ul
EUR 479

SOX2 Antibody

25044-100ul 100ul
EUR 468

SOX2 Antibody

31128-100ul 100ul
EUR 302.4

SOX2 Antibody

31128-50ul 50ul
EUR 224.4

SOX2 Antibody

48128 100ul
EUR 429

SOX2 Antibody

48128-100ul 100ul
EUR 399.6

SOX2 Antibody

48128-50ul 50ul
EUR 286.8

SOX2 Antibody

43142 100ul
EUR 319

SOX2 Antibody

43142-100ul 100ul
EUR 302.4

SOX2 antibody

38134-100ul 100ul
EUR 302.4

SOX2 Antibody

CSB-PA982860- each
EUR 402
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

SOX2 Antibody

CSB-PA982860-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

SOX2 Antibody

E031128 100μg/100μl
EUR 255
Description: Available in various conjugation types.

SOX2 Antibody

E021425 50μg/50μl
EUR 100
Description: Available in various conjugation types.

SOX2 Antibody

E043142 100μg/100μl
EUR 255
Description: Available in various conjugation types.

SOX2 Antibody

E10-20267 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E10-30144 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E18-4010-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

SOX2 Antibody

E18-4010-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E18-5140-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

SOX2 Antibody

E18-5140-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E19-6109 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E81106-1 100ul
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

1-CSB-PA022426GA01HU
  • Ask for price
  • Ask for price
  • 150ul
  • 50ul
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse, Rat, Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, IF

SOX2 Antibody

DF6109 200ul
EUR 420

SOX2 Antibody

DF6109-100ul 100ul
EUR 280

SOX2 Antibody

DF6109-200ul 200ul
EUR 350

SOX2 Antibody

E90561 100ul
EUR 255
Description: Available in various conjugation types.

SOX2 Antibody

E561026-A-SE 100ug
EUR 295
Description: Available in various conjugation types.

SOX2 Antibody

E561028-A-SE 100ug
EUR 295
Description: Available in various conjugation types.

SOX2 Antibody

E301925 200ul
EUR 275
Description: Available in various conjugation types.

SOX2 Antibody

E301926b 200ul
EUR 275
Description: Available in various conjugation types.

Sox2 Antibody

E220095-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Sox2 Antibody

E220095-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

E220170-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

SOX2 Antibody

E220170-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SOX2 Antibody

BF0481-100ul 100ul
EUR 350

SOX2 Antibody

BF0481-200ul 200ul
EUR 450

SOX2 Antibody

BF0481-50ul 50ul
EUR 250

SOX2 Antibody

CAC11873-100ul 100ul
EUR 367.5

SOX2 Antibody

CAC11873-50ul 50ul
EUR 252

SOX2 antibody

CAF50335-100ug 100ug
EUR 312

SOX2 Antibody

CAC07009-100ug 100ug
EUR 314

SOX2 Antibody

CAC07009-50ug 50ug
EUR 199.2

SOX2 antibody

70R-12166 100 ug
EUR 343
Description: Rabbit polyclonal SOX2 antibody

SOX2 antibody

70R-20460 50 ul
EUR 289
Description: Rabbit polyclonal SOX2 antibody

SOX2 antibody

70R-33158 100 ug
EUR 451
Description: Rabbit polyclonal SOX2 antibody

SOX2 antibody

70R-33160 100 ug
EUR 451
Description: Rabbit polyclonal SOX2 antibody

Sox2 antibody

70R-SR013 100 ug
EUR 280
Description: Affinity purified Rabbit polyclonal Sox2 antibody

SOX2 Antibody

5583-002mg 0.02 mg
EUR 206.18
Description: SOX2 Antibody: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX2 is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. The role of SOX2 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing SOX2 and the transcription factors POU5F1, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. Other experiments have shown that iPS cells could be generated using expression plasmids expressing POU5F1, SOX2, KlfF4 and c-Myc, eliminating the need for virus introduction.

SOX2 Antibody

5583-01mg 0.1 mg
EUR 523.7
Description: SOX2 Antibody: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX2 is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. The role of SOX2 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing SOX2 and the transcription factors POU5F1, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. Other experiments have shown that iPS cells could be generated using expression plasmids expressing POU5F1, SOX2, KlfF4 and c-Myc, eliminating the need for virus introduction.

SOX2 Antibody

AF5140 200ul
EUR 420

SOX2 Antibody

AF5140-100ul 100ul
EUR 280

SOX2 Antibody

AF5140-200ul 200ul
EUR 350

SOX2 Antibody

AF4010 200ul
EUR 540

SOX2 Antibody

AF4010-100ul 100ul
EUR 350

SOX2 Antibody

AF4010-200ul 200ul
EUR 450

SOX2 Antibody

AF4010-50ul 50ul
EUR 250

SOX2 Antibody

AF7950 200ul
EUR 540

SOX2 Antibody

AF7950-100ul 100ul
EUR 350

SOX2 Antibody

AF7950-200ul 200ul
EUR 450

SOX2 Antibody

AF7950-50ul 50ul
EUR 250

SOX2 Antibody

1-CSB-PA588368
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50

SOX2 Antibody

1-CSB-PA698932
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

SOX2 Antibody

1-CSB-PA16539A0Rb
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

SOX2 Antibody

ABD6109 100ug
EUR 325

SOX2 Antibody

ABF4010 100ug
EUR 325

SOX2 Antibody

ABF5140 100ug
EUR 325

SOX2 Antibody

F54738-0.08ML 0.08 ml
EUR 140.25
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

SOX2 Antibody

F54738-0.4ML 0.4 ml
EUR 322.15
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

SOX2 Antibody

F47908-0.08ML 0.08 ml
EUR 140.25
Description: The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

SOX2 Antibody

F47909-0.08ML 0.08 ml
EUR 140.25
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

SOX2 Antibody

F47909-0.4ML 0.4 ml
EUR 322.15
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

SOX2 Antibody

F49268-0.08ML 0.08 ml
EUR 140.25
Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.

SOX2 Antibody

F49268-0.4ML 0.4 ml
EUR 322.15
Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.

SOX2 Antibody

F40361-0.08ML 0.08 ml
EUR 140.25
Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

SOX2 Antibody

F40361-0.4ML 0.4 ml
EUR 330.65
Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

SOX2 Antibody

F52893-0.08ML 0.08 ml
EUR 140.25
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F52921-0.08ML 0.08 ml
EUR 140.25
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F52921-0.4ML 0.4 ml
EUR 322.15
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F52993-0.08ML 0.08 ml
EUR 140.25
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F52993-0.4ML 0.4 ml
EUR 322.15
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F53133-0.08ML 0.08 ml
EUR 140.25
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

F53133-0.4ML 0.4 ml
EUR 322.15
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

SOX2 Antibody

GWB-ML185E 50ug Ask for price

SOX2 Antibody

GWB-CF53BE 0.1 mg Ask for price

SOX2 Antibody

GWB-MM710H 50ug Ask for price

SOX2 Antibody

R20441-0.1ML 100ul
EUR 409

SOX2 Antibody

R31408 100 ug
EUR 356.15
Description: SRY (sex determining region Y)-box 2 is a transcription factor that is essential for maintaining self-renewal, or pluripotency of undifferentiated embryonic stem cells. The protein is a member of the Sox family of transcription factors, which have been shown to play key roles in many stages of mammalian development. It was found that SOX2 can regulate OCT3/4 expression and maintains ES pluripotency through upstream transcription factors. It is identified as a lineage-survival oncogene in lung and esophageal squamous cell carcinoma. In addition to those, it has a critical role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine.

SOX2 Antibody

V7863-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V7863-20UG 20 ug
EUR 153.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V7863SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V7864-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V7864-20UG 20 ug
EUR 153.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V7864SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8085-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8085-20UG 20 ug
EUR 153.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8085SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8086-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8086-20UG 20 ug
EUR 153.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V8086SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

SOX2 Antibody

V3385-100UG 100 ug
EUR 349.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3385-20UG 20 ug
EUR 153.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3385IHC-7ML 7 ml
EUR 424.15
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3385SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3386-100UG 100 ug
EUR 349.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3386-20UG 20 ug
EUR 153.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3386IHC-7ML 7 ml
EUR 424.15
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V3386SAF-100UG 100 ug
EUR 349.3
Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.

SOX2 Antibody

V7640-100UG 100 ug
EUR 349.3
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]

SOX2 Antibody

V7640-20UG 20 ug
EUR 153.3
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]

SOX2 Antibody

V7640SAF-100UG 100 ug
EUR 349.3
Description: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [UniProt]

SOX2 antibody

BF0481 100ug
EUR 355

SOX2 Antibody

MBS7136837-005mL 0.05mL
EUR 220

SOX2 Antibody

MBS7136837-01mL 0.1mL
EUR 300

SOX2 Antibody

MBS7136837-5x01mL 5x0.1mL
EUR 1350

SOX2 Antibody

MBS7130456-01mL 0.1mL
EUR 270

SOX2 Antibody

MBS7130456-5x01mL 5x0.1mL
EUR 1200

SOX2 Antibody

MBS7124294-005mL 0.05mL
EUR 190

SOX2 Antibody

MBS7124294-01mL 0.1mL
EUR 270

SOX2 Antibody

MBS7124294-5x01mL 5x0.1mL
EUR 1205

SOX2 Antibody

MBS7124295-005mL 0.05mL
EUR 190

SOX2 Antibody

MBS7124295-01mL 0.1mL
EUR 270

SOX2 Antibody

MBS7124295-5x01mL 5x0.1mL
EUR 1205

SOX2 Antibody

MBS9408981-005mL 0.05mL
EUR 245

SOX2 Antibody

MBS9408981-01mL 0.1mL
EUR 305

SOX2 Antibody

MBS9408981-5x01mL 5x0.1mL
EUR 1230

SOX2 antibody

MBS9414286-005mL 0.05mL
EUR 300

SOX2 antibody

MBS9414286-01mL 0.1mL
EUR 390

SOX2 antibody

MBS9414286-5x01mL 5x0.1mL
EUR 1610

SOX2 Antibody

MBS9407333-01mL 0.1mL
EUR 305

SOX2 Antibody

MBS9407333-5x01mL 5x0.1mL
EUR 1230

SOX2 Antibody

MBS9411742-01mL 0.1mL
EUR 495

SOX2 Antibody

MBS9411742-5x01mL 5x0.1mL
EUR 2075

SOX2 Antibody

MBS9224515-INQUIRE INQUIRE Ask for price

SOX2 Antibody

MBS858633-01mg 0.1mg
EUR 370

SOX2 Antibody

MBS858633-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS858633-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS858633-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS858633-01mLAF635 0.1mL(AF635)
EUR 565

SOX2 Antibody

MBS859182-01mg 0.1mg
EUR 370

SOX2 Antibody

MBS859182-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS859182-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS859182-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS859182-01mLAF635 0.1mL(AF635)
EUR 565

SOX2 Antibody

MBS9211837-008mL 0.08mL
EUR 210

SOX2 Antibody

MBS9211837-04mL 0.4mL
EUR 430

SOX2 Antibody

MBS9211837-5x04mL 5x0.4mL
EUR 1910

Sox2 Antibody

MBS9215547-01mL 0.1mL
EUR 425

Sox2 Antibody

MBS9215547-5x01mL 5x0.1mL
EUR 1887

SOX2 Antibody

MBS9200597-008mL 0.08mL
EUR 210

SOX2 Antibody

MBS9200597-04mL 0.4mL
EUR 430

SOX2 Antibody

MBS9200597-5x04mL 5x0.4mL
EUR 1910

SOX2 Antibody

MBS857011-01mL 0.1mL
EUR 305

SOX2 Antibody

MBS857011-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS857011-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS857011-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS857011-01mLAF635 0.1mL(AF635)
EUR 565

SOX2 Antibody

MBS8504836-01mL 0.1mL
EUR 325

SOX2 Antibody

MBS8504836-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS8504836-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS8504836-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS8504836-01mLAF635 0.1mL(AF635)
EUR 565

SOX2 Antibody

MBS850914-01mg 0.1mg
EUR 305

SOX2 Antibody

MBS850914-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS850914-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS850914-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS850914-01mLAF635 0.1mL(AF635)
EUR 565

Sox2 Antibody

MBS851014-005mg 0.05mg
EUR 235

Sox2 Antibody

MBS851014-01mg 0.1mg
EUR 305

Sox2 Antibody

MBS851014-01mLAF405L 0.1mL(AF405L)
EUR 565

Sox2 Antibody

MBS851014-01mLAF405S 0.1mL(AF405S)
EUR 565

Sox2 Antibody

MBS851014-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS8511684-005mg 0.05mg
EUR 235

SOX2 Antibody

MBS8511684-01mg 0.1mg
EUR 305

SOX2 Antibody

MBS8511684-01mLAF405M 0.1mL(AF405M)
EUR 465

SOX2 Antibody

MBS8511684-01mLAF546 0.1mL(AF546)
EUR 465

SOX2 Antibody

MBS8511684-01mLAF750 0.1mL(AF750)
EUR 465

SOX2 Antibody

MBS8511771-005mg 0.05mg
EUR 235

SOX2 Antibody

MBS8511771-01mg 0.1mg
EUR 305

SOX2 Antibody

MBS8511771-01mLAF405M 0.1mL(AF405M)
EUR 465

SOX2 Antibody

MBS8511771-01mLAF546 0.1mL(AF546)
EUR 465

SOX2 Antibody

MBS8511771-01mLAF750 0.1mL(AF750)
EUR 465

SOX2 Antibody

MBS8516026-01mg 0.1mg
EUR 305

SOX2 Antibody

MBS8516026-01mLAF405L 0.1mL(AF405L)
EUR 465

SOX2 Antibody

MBS8516026-01mLAF405S 0.1mL(AF405S)
EUR 465

SOX2 Antibody

MBS8516026-01mLAF610 0.1mL(AF610)
EUR 465

SOX2 Antibody

MBS8516026-01mLAF635 0.1mL(AF635)
EUR 465

SOX2 Antibody

MBS850031-01mg 0.1mg
EUR 305

SOX2 Antibody

MBS850031-01mLAF405L 0.1mL(AF405L)
EUR 565

SOX2 Antibody

MBS850031-01mLAF405S 0.1mL(AF405S)
EUR 565

SOX2 Antibody

MBS850031-01mLAF610 0.1mL(AF610)
EUR 565

SOX2 Antibody

MBS850031-01mLAF635 0.1mL(AF635)
EUR 565

Sox2 Antibody

MBS8501326-01mL 0.1mL
EUR 305

Sox2 Antibody

MBS8501326-01mLAF405L 0.1mL(AF405L)
EUR 565

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